Hallmark
Nocturnal numbness and tingling in the median distribution, waking them, relieved by shaking the hand (the flick sign). Later: dropping things, thenar wasting, and reduced pinch. Sensation and pain can be normal by day, which is why the history carries the diagnosis.
Tests
- Phalen — hold both wrists in full flexion for 60 seconds. Positive: tingling in the median distribution.
- Durkan (carpal compression) — press directly over the carpal tunnel for 30 seconds. Positive: provoked symptoms. Generally the better performer of the two.
- Tinel at the carpal tunnel — Positive: tingling into the median distribution.weak; frequently positive in normal hands
- Thenar bulk, two-point discrimination, and pinch strength — Positive: atrophy or sensory loss → established compression, not early disease. This changes urgency.
- Screen the neck, elbow and forearm — median symptoms can come from a C6–C7 root or a proximal compression. Do not inject a wrist before you have screened above it.
Next: diagnosis is clinical and confirmed with nerve conduction studies when the answer matters — before surgery, or when there is motor loss. Night splints and corticosteroid injection work early; thenar wasting is the point of no return.